Colorectal cancer is cancer of the colon or rectum. Almost 150,000 U.S. men and women a year are estimated to have colorectal cancer, and as many as 55,000 die from it.
Colorectal cancer is one of the most preventable cancers since it typically develops from polyps that can be detected and removed before they become cancerous.
Reduce Your Risk
Colorectal cancer is one of the most preventable cancers.
Screening can find colorectal cancer early, when treatment works best. The most effective way to reduce your risk is by having regular colorectal cancer screenings beginning at age 45.
Increase your physical activity and maintain a healthy weight. Both of these may decrease your risk for colorectal cancer.
Eat a diet rich in fruits, vegetables and whole grains. A healthy diet can reduce your risk of colon cancer as well as other cancers, and works to improve your overall health. More about a healthy eating plan
Mississippians Speak
Gastroenterologist Samuel Pace, M.D., talks about his personal experience with colon cancer and the importance of screening. View full size
At Risk
For men and women with an average colorectal cancer risk, screening should begin at age 45.
Some people are at higher risk, and should talk to their doctor about the right screening schedule for them.
- People with a personal or family history of colorectal cancer or benign (not cancerous) colorectal polyps
- People with a personal or family history of inflammatory bowel disease, ulcerative colitis or Crohn's disease
- People who use tobacco
- People who are obese or sedentary
Mississippi led the nation in the rate of colorectal cancer deaths in 2023.

Symptoms
Symptoms are your best early warning of possible cancer. Early detection means that treatment has a greater chance of being successful, increasing your odds of a longer and healthier life. Discuss any of these symptoms with your doctor if they are prolonged.
Symptoms of colorectal cancer include:
- Rectal bleeding
- Blood in or on the stool (bright red)
- Change in bowel habits
- Stools that are narrower than usual
- Diarrhea, constipation or feeling that the bowel does not empty completely
- Weight loss for no apparent reason
- Constant tiredness
Screening
Men and women at average risk should begin regular screening at age 45. If you are at greater risk, you may need to begin regular colorectal cancer screening at an earlier age.
Screening saves lives. Early detection can find signs of colon or rectal cancer before it becomes life-threatening, when treatment is simple and effective. Screening is the best investment for your health.
James Rasberry, a Mississippi colon cancer survivor, talks about his cancer discovery and the importance of screening. View full size

